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on oral treatment with cyclosporine. Recommend a dosing regimen that would achieve free
steady state concentrations of 40 and 15 ng/mL. Cyclosporine is available in oral doses of 25mg and 100-mg. Calculate the anticipated total cyclosporine plasma concentrations (in
ng/mL) based on dosing regimen that you suggest. You may assume a rapid absorption
process and, thus, use the equations for IV bolus administration. Page 4 of 6 ( (
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- Spring '08