Unformatted text preview: CYDCCDK4
CDK2 E2F p21 p-p53
BAX DCT, TYR,
and PDE4D caspase
Apoptosis 25 Cellular Structure 26 Tissue and organs • Tissue – Group of cells with similar structure or func2on • Epithelial, connec2ve, nervous and muscle • Organs – Collec2on of two or more 2ssues that performs a physiological func2on 27 Mul2cellular Organisms • Single organisms composed of more than one cell • Main beneﬁt from the division of labor • Each cell have a diﬀerent func2on and therefore diﬀerent shape • Specialized cells need to be able to communicate and a^ached to adjacent cells 28 Mul2cellular Organisms • Have Extracellular Matrix (ECM) that provides support and connect cells • Cells junc2ons connect cells with each others and to ECM • Between ECM, cell junc2ons and adhesive molecules keeps mul2cellular organisms together 29 Extracellular Matrix (ECM) • Extracellular matrix helps to support and organize cells • Major component are proteins and polysaccharides • Roles –
– strength structure Support organiza2on cell signaling 30 Proteins of the extracellular matrix • Adhesive – Fibronec2n and laminin • Structur...
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