Lecture 2 - Cell organization function and communication

Lecture 2 - Cell organization function and communication -...

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Lecture’2:’ Cell’organiza±on,’func±on’and’communica±on’ BIOS E-1B Introduc±on’to’Organismic’and’Evolu±onary’Biology’ January’29,’2014’ Reading :’ Chapter’9’ Chapter’10’ 1’
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Announcements’ Discussion’Forum’ 2’
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Announcements’ Laboratory’sec2ons’ Sec2oning’will’start’next’Monday’at’10pm’ To’be’able’to’sing-in’for’a’laboratory’2me,’go’to’the’ laboratory’sec2on’on’the’class’website’and’look’for’the’ sec2oning’link’ Possible’sec2ons:’ 3’Mondays’6:40-9:40pm’ ±’Mondays’7:40-9:40pm’ ±’Wednesday’6:40-9:40pm’ 3’Wednesday’7:40-10:40pm’ 3’
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Announcements’ Change’in’discussion’sec2on’ Sec2ons’will’be’held’on’Monday,’Tuesday’or’ Wednesday’from’ 6:00-7:00pm at Science Center B-10 We’eliminated’Friday’6-7pm’sec2on’ We’opened’a’Saturday’11am-1±pm’sec2on’ Loca2on’TBA’ 4’
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Learning’Goals’and’Objec2ves’ Goal:’to’understand’how’cells’respond’to’environmental’cues’ Compare’and’contrast’the’diferent’signaling’pathways’ Given’a’par2cular’pathway,’iden2Fy’the’type’oF’signaling’and’the’transduc2on’process’ Goal:’to’understand’the’elements’that’compose’the’cellular’structure’ Iden2Fy’and’characterize’the’Func2on’and’components’oF’Extracellular’Matrix’(ECM)’ Given’a’par2cular’subcellular’structure,’iden2Fy’how’proteins’involved’interact’with’ one’another’and’how’they’conFer’Func2on’ ±or’each’type’oF’cell’junc2on,’outline’the’proteins’involved’and’Func2on’ Compare’and’contrast’how’the’diferent’proteins’involved’in’cell’junc2ons’conFer’ cellular’Func2on’ Outline’diferent’proteins’involved’in’the’cytoskeleton’ Goal:’to’understand’bene²ts/drawbacks’oF’molecular’biology’techniques’used’to’ detect’genes’at’the’transcrip2onal’and’transla2onal’level’ Given’a’speci²c’problem,’provide’a’technique’that’can’be’used’to’answer’the’ ques2on’ Iden2Fy’the’bene²ts’and’drawbacks’oF’the’molecular’biology’techniques’ discussed’in’lecture’ 5’
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Cell’communica2on’ 6’
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Cell’Signaling’ h^p://www.youtube.com/watch?v=JnlULOjUhSQ Cells’need’to’be’able’to’respond’to’environmental’cues’ Cell’signaling’-’Cytoskeleton’–’Cellular’movement’ 7’
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Signaling’pathway ’ ’ A’cell’releases’a’signal’(Signaling’cell),’which’ can’be’a’small’pep2de’or’a’small’molecule’ The’signal’binds’to’a’receptor’in’an’adjacent/ same’cell’(Responding’cell)’
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