Lecture 6 - Cardiovascular and Respiratory Systems

Circulatory system purpose to transport things along

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Unformatted text preview: body’s necessi7es •  Firing of respiratory motor neurons will indicate the diaphragm to contract and exhala7on begins •  As they stop firing, the diaphragm relaxes and inhala7on proceeds –  At rest it is a passive process, recoil/elas7city of lung 7ssue •  Mammals are insensi7ve to falling levels of O2 but highly sensi7ve to increased levels of CO2 –  Reverse for water animals –  Chemosensitve cells respond to increased levels of H+ (high CO223 ) Gas poisons •  CO intoxica7on –  CO is colorless and odorless –  240 ­fold higher affinity than O2 •  Treatment: 100% oxygen 24 Sickle cell anemia •  Hereditary blood disease •  Muta7on in the hemoglobin gene –  Homozygous recessive cannot survive –  Heterozygous have an advantage against malaria 25 Cys7c Fibrosis •  Cys7c Fibrosis –  Autosomal recessive gene7c disorder –  Abnormal transport of chloride and sodium across an epithelium –  Increased mucus in the respiratory track •  Difficulty in breathing caused by con7nuous lung infec7ons 26 Pulmonary condi7ons •  Asthma –  Muscles around bronchioles are hyperexcitable; contract more than usual –  May have gene7c basis •  Smoking –  One of leading global causes of death –  Up to 85% of all new cases...
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