Lecture 6 - Cardiovascular and Respiratory Systems

Lecture 6 Cardiovascular and Respiratory Systems

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Unformatted text preview: ffect (higher O2 pressure for 100% satura7on) 19 Oxygen carrying molecules •  Myoglobin has a higher binding affinity to O2 •  Will only release oxygen afer hemoglobin releases its bound O2 (oxygen reserve) 20 Oxygen carrying molecules •  Factors that affect hemoglobin’s ability to bind oxygen –  Chemical proper7es •  Fetal versus mother hemoglobin allows the release of oxygen from the mother’s blood –  pH •  Exercise byproducts (CO2 and lac7c acid) will decrease pH, H+ binds to hemoglobin and decreases it’s oxygen binding affinity –  2,3 ­bisphosphoglyceric acid (BPG) •  Glycolysis byproduct, decreases O2 binding affinity •  Increases with sudden exercise or increased al7tude 21 CO2 transporta7on •  Most CO2 is carried in the blood as bicarbonate ions CO2 + H2O H2CO3 H+ + HCO3- • Concentra7on of hydrogen ions in the blood reflects the amount of carbon dioxide produced by cells during metabolism 22 Control of breathing by CNS •  Autonomic nervous system controls breathing and modifies it according to...
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This document was uploaded on 03/05/2014.

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