Human Genome Sequence

2 billion base pair human genome chimpanzees share 95

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Unformatted text preview: large percentage (over 50%) of human genome. • Protein- coding genes make up about 24,000, less than 2% of the 3.2 billion base pair human genome. • Chimpanzees share 95% of the human genome. • Evolution of the genome • Single nucleotide polymorphism (SNPs): DNA sequence variation that involve single nucleotides. o Haplotype maps are based on them o Rapid genotyping technology o SNPs are point mutations in a DNA sequence. o Change of a single base pair (SNP) which can make a big difference in someone’s phenotype. • Pharmacogenomics o Someone’s genotype can affect their response to a particular drug o Makes it possible to predict whether a drug will be effective with the objective of personalizing drug treatment o Know what to prescribe so you don’t have to try like a whole bunch of medication • DNA fingerprinting o Group of techniques used to identify individuals by their DNA o We can use SNPs o We can also use Short Tandem Repeats (STR) §༊ Most common §༊ Used in paternity test and investigating crime §༊ When several different STR loci are analyzed, a unique pattern becomes apparent • There is a single gene in dogs (IGF- 1) that determines size....
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This document was uploaded on 03/06/2014 for the course BIO 020.151 at Johns Hopkins.

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