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Unformatted text preview: ), the complex 3dimensional structure of the protein
spontaneously unfolds. Pressure remains at 1 atm throughout, and assume
heat capacities are independent of temperature. In addition, you are given
the following data:
∆H° = +1000 kJ/mol for unfolding reaction (independent of temperature)
Cpunfolded  Cpfolded = 6.28 kJ/mol/K (independent of temperature)
1.If the transition temperature represents the point where the folded and
unfolded albumin are at equilibrium, calculate the entropy of unfolding at
69°C.
2.Defining the system as albumin only, does disorder in the system
increases or decreases when albumin unfolds and why?
3.Calculate the entropy of unfolding at 25°C.
a. First, draw a 3step process that would make use of your result from
part (a).
b. Second, calculate the entropy of unfolding at 25°C. Sample Problem 5:
Effect of Temperature on Water Evaporation
1. Calculate the change in Gibbs free energy for water
going from liquid at 35°C to vapor at 35°C. Use data
from the tables at the back of the book, and assume
that the e...
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This document was uploaded on 03/03/2014.
 Spring '14

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