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Unformatted text preview: ), the complex 3-dimensional structure of the protein
spontaneously unfolds. Pressure remains at 1 atm throughout, and assume
heat capacities are independent of temperature. In addition, you are given
the following data:
∆H° = +1000 kJ/mol for unfolding reaction (independent of temperature)
Cpunfolded - Cpfolded = 6.28 kJ/mol/K (independent of temperature)
1.If the transition temperature represents the point where the folded and
unfolded albumin are at equilibrium, calculate the entropy of unfolding at
2.Defining the system as albumin only, does disorder in the system
increases or decreases when albumin unfolds and why?
3.Calculate the entropy of unfolding at 25°C.
a. First, draw a 3-step process that would make use of your result from
b. Second, calculate the entropy of unfolding at 25°C. Sample Problem 5:
Effect of Temperature on Water Evaporation
1. Calculate the change in Gibbs free energy for water
going from liquid at 35°C to vapor at 35°C. Use data
from the tables at the back of the book, and assume
that the e...
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This document was uploaded on 03/03/2014.
- Spring '14