6 cancers usually arise due to mutations in the genes

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Unformatted text preview: e. 6. Cancers usually arise due to mutations in the genes encoding critical cell signaling proteins. Often, these mutations disrupt (i.e., destabilize) the structure of molecular switch elements that normally ensure the proper response of the cell to its environment. A study of patient biopsies showed that 40% of patients suffering from a particular kind of lung cancer had a single point mutation at a specific site in the gene for a signaling protein known as the epidermal growth factor (EGF) receptor. This mutation resulted in the replacement of the leucine residue normally present at this position by arginin...
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This homework help was uploaded on 03/05/2014 for the course MCB 100A taught by Professor Kuryian during the Fall '09 term at University of California, Berkeley.

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