This preview shows page 1. Sign up to view the full content.
Unformatted text preview: e.
6. Cancers usually arise due to mutations in the genes encoding critical cell signaling proteins.
Often, these mutations disrupt (i.e., destabilize) the structure of molecular switch elements that
normally ensure the proper response of the cell to its environment. A study of patient biopsies
showed that 40% of patients suffering from a particular kind of lung cancer had a single point
mutation at a specific site in the gene for a signaling protein known as the epidermal growth
factor (EGF) receptor. This mutation resulted in the replacement of the leucine residue normally
present at this position by arginin...
View Full Document
This homework help was uploaded on 03/05/2014 for the course MCB 100A taught by Professor Kuryian during the Fall '09 term at University of California, Berkeley.
- Fall '09