Problem Set 1 - Problem Set 1 CHEM-130/MCB-100A Fall 2013...

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Instructors: John Kuriyan & David Wemmer Problem Set 1. Due Thursday, September 5 at the beginning of class. READING: Chapter 1, The Molecules of Life. Also, begin reading Chapter 4. The problem sets in this course are an excellent way to review the material in a way that prepares you for the exams. You may consult any sources you wish to answer these questions, but make sure that you work through the questions and understand your answers. Please work through all of the questions at the end of Chapter 1 of The Molecules of Life, as well as the additional 10 questions given below. This problem set reviews basic biochemical principles, which should be familiar from an introductory biology class, such as Bio 1A at Berkeley. Hand in the answers to the following 5 problems in class. Put your name and that of your GSI on the solutions turned in. All answers must by handwritten in order to be graded. Chapter 1 Q3, Q17, Q19, Additional Question 2, Additional Q9. 1. List polymer molecules that are found in living systems. Which of these bear a direct relationship to the genetic code? 2. Consider the oxygen atom of a carboxyl sidechain (such as in Asp and Glu residues) interacting with the NH2 group of an arginine sidechain. Roughly speaking, explain what happens to the
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