The Oncologist-2004-Perlis-182-7

Proc natl acad sci usa 20031001221 1225 187 recent

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Unformatted text preview: roc Natl Acad Sci USA 2003;100:1221-1225. 187 Recent Advances in Melanoma Biology 23 Atillasoy ES, Seykora JT, Soballe PW et al. UVB induces atypical melanocytic lesions and melanoma in human skin. Am J Pathol 1998;152:1179-1186. 34 Xie S, Luca M, Huang S et al. Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis. Cancer Res 1997;57:2295-2303. 24 Smalley KS. A pivotal role for ERK in the oncogenic behaviour of malignant melanoma? Int J Cancer 2003;104:527-532. 35 Hsu MY, Wheelock MJ, Johnson KR et al. Shifts in cadherin profiles between human normal melanocytes and melanomas. J Investig Dermatol Symp Proc 1996;1:188-194. 25 Hingorani SR, Jacobetz MA, Robertson G et al. Suppression of brafv599e in human melanoma abrogates transformation. Cancer Res 2003;63:5198-5202. 26 Davies H, Bignell GR, Cox C et al. Mutations of the BRAF gene in human cancer. Nature 2002;417:949-954. 27 Brose MS, Volpe P, Feldman M et al. BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res 2002;62:6997-7000. 28 Satyamoorthy K, Li G, Gerrero MR et al. Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation. Cancer Res 2003;63:756-759. 29 Satyamoorthy K, Li G, Vaidya B et al. Insulin-like growth factor1 induces survival and growth in biologically early melanoma cells through both the mitogen-activated protein kinase and beta-catenin pathways. Cancer Res 2001;61:7318-7324. 30 Pollock PM, Harper UL, Hansen KS et al. High frequency of BRAF mutations in nevi. Nat Genet 2003;33:19-20. 31 Meier F, Satyamoorthy K, Nesbit M et al. Molecular events in melanoma development and progression. Front Biosci 1998;3:D1005-D1010. 32 Clark WH. Tumour progression and the nature of cancer. Br J Cancer 1991;64:631-644. 33 Danen EH, de Vries TJ, Morandini R et al. E-cadherin expression in human melanoma. Melanoma Res 1996;6:127-131. 36 Tang A, Eller MS, Hara M et al. E-cadherin is the major mediator of human melanocyte adhesion to keratinocytes in vitro. J Cell Sci 1994;107:983-992. 37 Hsu MY, Meier FE, Nesbit M et al. E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors. Am J Pathol 2000;156:1515-1525. 38 Li G, Satyamoorthy K, Herlyn M. N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells. Cancer Res 2001;61:3819-3825. 39 Sturm RA, Satyamoorthy K, Meier F et al. Osteonectin/SPARC induction by ectopic β3 integrin in human radial growth phase primary melanoma cells. Cancer Res 2002;62:226-232. 40 Hsu MY, Shih DT, Meier FE et al. Adenoviral gene transfer of β3 integrin subunit induces conversion from radial to vertical growth phase in primary human melanoma. Am J Pathol 1998;153:14351442. 41 Li G, Kalabis J, Xu X et al. Reciprocal regulation of MelCAM and AKT in melanoma. Oncogene 2003;22:6891-6899. 42 Liu ZJ, Snyder R, Souma A et al. VEGF-A and alphaVbeta3 integrin synergistically rescue angiogenesis via N-Ras and PI3K signaling in human microvascular endothelial cells. FASEB J 2003;17:1931-1933. 43 Gutheil JC, Campbell TN, Pierce PR et al. Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin αvβ3. Clin Cancer Res 2000;6:3056-3061....
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