New Perspectives on Melanoma_ The Role of PAX3

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Unformatted text preview: ign and Malignant Tissues of the Melanocytic Lineage in Humans. J Invest Dermatol. 19. Lang D, Lu MM, Huang L, Engleka KA, Zhang M, et al. (2005) Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature 433: 884‐887. 113 References 20. Yang G, Li Y, Nishimura EK, Xin H, Zhou A, et al. (2008) Inhibition of PAX3 by TGF‐beta modulates melanocyte viability. Mol Cell 32: 554‐563. 21. Barr FG, Fitzgerald JC, Ginsberg JP, Vanella ML, Davis RJ, et al. (1999) Predominant expression of alternative PAX3 and PAX7 forms in myogenic and neural tumor cell lines. Cancer Res 59: 5443‐5448. 22. Koyanagi K, Kuo C, Nakagawa T, Mori T, Ueno H, et al. (2005) Multimarker quantitative real‐time PCR detection of circulating melanoma cells in peripheral blood: relation to disease stage in melanoma patients. Clin Chem 51: 981‐988. 23. Muratovska A, Zhou C, He S, Goodyer P, Eccles MR (2003) Paired‐Box genes are frequently expressed in cancer and often required for cancer cell survival. Oncogene 22: 7989‐7997. 24. Plummer RS, Shea CR, Nelson M, Powell SK, Freeman DM, et al. (2008) PAX3 expression in primary melanomas and nevi. Mod Pathol 21: 525‐530. 25. Scholl FA, Kamarashev J, Murmann OV, Geertsen R, Dummer R, et al. (2001) PAX3 is expressed in human melanomas and contributes to tumor cell survival. Cancer Res 61: 823‐826. 26. Takeuchi H, Morton DL, Kuo C, Turner RR, Elashoff D, et al. (2004) Prognostic significance of molecular upstaging of paraffin‐embedded sentinel lymph nodes in melanoma patients. J Clin Oncol 22: 2671‐2680. 27. He S, Li CG, Slobbe L, Glover A, Marshall E, et al. (2010) PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression. Melanoma Res. 28. He SJ, Stevens G, Braithwaite AW, Eccles MR (2005) Transfection of melanoma cells with antisense PAX3 oligonucleotides additively complements cisplatin‐induced cytotoxicity. Mol Cancer Ther 4: 996‐1003. 29. Hoek KS, Goding CR (2010) Cancer stem cells versus phenotype‐switching...
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