New Perspectives on Melanoma_ The Role of PAX3


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Unformatted text preview: n ideal model to study cellular differentiation. Pigment Cell Res 16: 237‐244. 191. Nishikawa S, Osawa M (2007) Generating quiescent stem cells. Pigment Cell Res 20: 263‐270. 192.Ohyama M, Terunuma A, Tock CL, Radonovich MF, Pise‐Masison CA, et al. (2006) Characterization and isolation of stem cell‐enriched human hair follicle bulge cells. J Clin Invest 116: 249‐260. 193. Carreira S, Goodall J, Denat L, Rodriguez M, Nuciforo P, et al. (2006) Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. Genes Dev 20: 3426‐3439. 194. Moriyama M, Osawa M, Mak SS, Ohtsuka T, Yamamoto N, et al. (2006) Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol 173: 333‐339. 195. Epstein DJ, Vekemans M, Gros P (1991) Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax‐3. Cell 67: 767‐774. 196. Carreira S, Goodall J, Aksan I, La Rocca SA, Galibert MD, et al. (2005) Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression. Nature 433: 764‐769. 197. Li HG, Wang Q, Li HM, Kumar S, Parker C, et al. (2007) PAX3 and PAX3‐FKHR promote rhabdomyosarcoma cell survival through downregulation of PTEN. Cancer Lett 253: 215‐223. 198. Freeman DJ, Li AG, Wei G, Li HH, Kertesz N, et al. (2003) PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase‐ dependent and ‐independent mechanisms. Cancer Cell 3: 117‐130. 199. Zhou M, Gu L, Findley HW, Jiang R, Woods WG (2003) PTEN reverses MDM2‐ mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells. Cancer Res 63: 6357‐6362. 200. Lang D, Epstein JA (2003) Sox10 and Pax3 physically interact to mediate activation of a conserved c‐RET enhancer. Hum Mol Genet 12: 937‐945. 201. Lang D, Chen F, Milewski R, Li J, Lu MM, et al. (2000) Pax3 is required for enteric ganglia formation and functions with Sox10 to modulate expression of c‐ret. J Clin Invest 106: 963‐971. 202. Epstein...
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