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Unformatted text preview: eq for the sum of the two reactions: Glucose 1phosphate ——>
Fructose 6phosphate.
G’º for both reactions can be found the the Biochemistry book Table 13.4. ln k"eq = G'/RT
= (5.6kJ/mol)/(2.48 kJ/mol) = 2.3
Keq = 10 5. (15%) Effect of [ATP]/[ADP] Ratio on Free Energy of Hydrolysis of ATP. Plot G against ln Q
(massaction ratio) at 25 ºC for the concentrations of ATP/ADP and Pi from the table indicated below. Gº for
the reaction is 30.5 kJ/mol. Use the resulting plot to explain why metabolism is regulated to keep the ratio
[ATP]/[ADP] high.
(plot separately uploaded) ln Q 1 = ln [(2 x 10^4)(1 x 10 ^2)/(5 x 10^3)] = 7.8
ln Q2 = ln [(2.2 x 10 ^3)(1.21 x 10 ^2)/(3 x 10 ^3)] = 4.7
ln Q3 = ln [(4.2 x 10^3)(1.41 x 10^2)/(1x10^3)] = 2.8
ln Q4 = ln [(5 x 10^3)(1.49 x 10 ^2)/(2 x 10 ^4)] = 1.0
ln Q5 = ln[(2.5 x 10^2)(1 x 10^2)(5x10^3)] = 3.0
G1 =
G2 =
G3 =
G4 =
G5 = The G for ATP hydrolysis is
smaller wen [ATP/ADP] is low
(<1) than when [ATP]/[ADP] is
high. The energy available to a...
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This document was uploaded on 03/06/2014.
 Spring '14

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