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Genetics HW#5 - during mammalian embryogenesis These X...

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How could you explain a tortoiseshell cat that is a male? In your answer consider the likely sex chromosome content of this male cat, and its complement of black and orange coat color alleles. (Hint: see p 177 of your textbook). It is possible to have a tortoiseshell cat this is male because it can have an XXY sex chromosome. This condition is called Klinefelter’s syndrome. According to the Lyon Hypothesis, in cells with multiple X chromosomes, all but one chromosome is inactivated
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Unformatted text preview: during mammalian embryogenesis. These X chromosomes are turned into inactive Barr bodies. Therefore the heterozygous XXY male would show patches of orange and black. This pigmentation of these heterozygous males is mottled with large patches expressed on one X chromosome and other patches expressed on the other. This results if different X chromosomes were inactive in adjacent patches of cells....
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