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Skip skip nod nucelotide binding oligomerization

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Unformatted text preview: ding oligomerization domain) also has a caspase recruiting domain (CARD) Activation of some TLRs and NODs can lead to the production of IL-1, IL-18 and IL-33 in macrophages. Roles of Mast Cells, Neutrophils, Eosinophils ,in inflamma7on and the innate immune response Neutrophils produce a bunch of organisms * * Lactoferrin shows in milk. binds to iron. protected to the host. lactoferrin binds to the iron with the bacteria and thus deprives the invaders it out competes the bacteria for iron. Bactericidal products produced by neutrophils skip mast cell binds to the worm. by the antibody variable region binding to the worm and then the constant region goes to the mast cell * * * * * * Degranulation via IgE and C3a and C5a Mast Cell Products * * * * * * * Role of Eosinophils ADCC via IgG and IgE; activated by Mast Cells Role of Chemokines in Innate Immunity and Inflamma7on skip Chemokine Structure (CXCL8) (blue cylinders represent alpha helices) Chemokine Receptor (generic) G protein affiliated GDP and turn it to GTP=GA...
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