Unformatted text preview: chain. become the paratope/antibody. the only difference is that it is more
complex because it binds to the MHC and the anitbody. 3 cdrs for the alpha and 3 for the beta
CDR 1 and TCR binding to Class I and processed Ag. CDR 1 and 2 of β chain are light and
dark blue, respectively. CDR 1 and
2 of α chain are light and dark purple.
CDR 3 α chain is yellow; CDR 3 β
chain is green. HV4 of β chain is red. mch1 3 1 3 1
2 2 In b, CDR 1 and 2 of alpha chain lie
over amino end of bound peptide and
alpha 2 of MHC I whereas CDR 1 and
2 of beta chain of TCR lie over carboxy
end of peptide and alpha 1 of MHC I....
View Full Document
- Fall '12
- T Cell, Major histocompatibility complex, T cell receptor