This preview shows page 1. Sign up to view the full content.
Unformatted text preview: hloroquine inhibites class 2 and emetine inhibits class 1
infectious virus can affect class 1 and expressed along with class 2 being entocytosis and shown
it can not be produced in class 1 because the protein synthesis being blocked
same as thhe infectious virus with emetine
infectious virus and chloroquine, but if you put the gene in it and then presented in class 2
HA protein Treatment
Of Target Cells Class I Restricted Class II Restricted + + - + - + Infectious virus + chloroquine + - HA protein - + HA gene + + Infectious Virus
UV- Inactivated Virus
Infectious virus + emetine Chloroquine inhibits endocytic pathway; emetine inhibits protein synthesis
class 2 process Kuby et al 5th edition- Immunology class 1 Cross presentation, aka retrograde transolocation Cross presentation pathway
(membrane and secreted proteins) galactosyltransferase. lacks that enzyme, because any sugar(left) in the body the cell treats it as a foreign object. so we will have a lot
View Full Document
This document was uploaded on 03/10/2014 for the course BIOLOGY 104 at Tufts.
- Fall '12