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The degree of biological sophistication that allows

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Unformatted text preview: d molecular biology. The prerequisite for the course is 3 hours of organic chemistry with a grade of C or better. 1 Revised 1/4/2014 CH369: Fundamentals of Biochemistry Spring 2014 Unique #53050: TTh at 8:00- 9:30 am in WEL 1.316 II. Course Aims and Objectives: Aims Biochemistry is, in simplest terms, the study of the chemistry of living things. The general aim of this course, therefore, is to train students to understand biological processes and events by learning the logic of chemistry. It is far more than simply memorizing structures and pathways; the fascination of the field is to see how and why biological molecules are built the way they are and how this makes life possible – on many levels and with an amazing degree coordination and control. The degree of biological sophistication that allows you to read this document and (hopefully) make sense of it is truly amazing! Learning Objectives: General • Learn the language of biochemistry • Be thoroughly familiar with the dynamic nature of all living systems • Understand and be able to apply the principles of thermodynamics to biological systems • Understand the principles that relate to spontaneity in biological systems and be able to predict whether or not a given reaction or process will be spontaneous • Know the basic compartments within a living cell and how they relate to basic biochemical systems • Understand the be able to apply the principles that govern the use of various techniques in the study of biochemical systems • Understand the basic principles that govern the interaction of various biological molecules • Understand the importance of balance in biological systems and the consequences of imbalance in terms of human disease In order to make sense of the material in this course, you should be asking at least some of the following questions ALL of the time: • HOW is this built or HOW does this work (structure/order)? • WHY is it built or WHY does it work this way (function)? o WHAT IF it worked a different way (order)? • HOW does this allow it to perform its role in the cell (context)? • HOW does this interact with other molecules or processes (cross- talk)? • HOW is this molecule or process activated or inhibited (regulation)? • HOW well does this work (redundancy)? • HOW can I know if this is happening (detection)? • HOW can I measure this (quantitative/qualitative analysis)? When you have completed the course you should: Water • Understand the intricate role of water in all living systems and how the various biological molecules interact in an aqueous environment • Understand the principles t...
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