Know how to predict spontaneity based on g values or

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Unformatted text preview: o Intermediate between substrates and products o The higher the energy of the transition state – the higher the energy hill – the fewer molecules that can make it “over the hill” – the slower the reaction (less product per unit time) • Know how to predict spontaneity based on ΔG values or from the reaction diagram • Know the classes of cofactors that may be associated with enzymes o Metal ions are inorganic o Coenzymes are organic §༊ Cosubstrates §༊ Prosthetic groups • Understand the three types of catalytic mechanisms and how they work o Acid- base catalysis o Metal ion catalysis o Covalent catalysis • Be able to recognize which amino acid residues might participate in the different types of catalysis and why • Know the specific...
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