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Aureus than from hivaids ca mrsa strains seem more

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Unformatted text preview: associated infec6ons (CA- MRSA and HA- MRSA) ü༏  In 2005, ~95,000 people developed an invasive MRSA infec6on ü༏  Nearly 19,000 people died from invasive MRSA in 2005 ü༏  In the USA more people die from S. aureus than from HIV/AIDS ü༏  CA- MRSA strains seem more virulent than HA- MRSA (animal models) hIp:// for- mrsa.jpg Klevens RM et al JAMA. 2007 Oct 17;298(15):1763- 71. Deleo FR et al Lancet. 2010 May 1;375(9725):1557- 68. Voyich JM et al J. Immunol. 2005 Sep 15;175(6):3907- 19. The Emergence Of Methicillin Resistant Staphylococcus aureus (MRSA) S. aureus Infections In US Hospitals Source: AHRQ, Center for Delivery, Organiza6on, and Markets, Healthcare Cost and U6liza6on Project, Na6onwide Inpa6ent Sample, 1993–2005. From: Infec6ons with Methicillin- Resistant Staphylococcus Aureus (MRSA) in U.S. Hospitals, 1993–2005 Abscesses: A Hallmark Of S. aureus Infec-ons What Virulence Factors Contribute To S. aureus’ Avoidance of Phagocytes- Mediated Killing? 7 ü༏  ü༏  ü༏  ü༏  Panton- Valen6ne leukocidin (LukSF- PV/PVL) γ- hemolysin (HlgAB &...
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This document was uploaded on 03/09/2014 for the course BIOLOGY biocore at NYU.

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