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Unformatted text preview: escendant of people who don't drink milk as adult.
They become lactose-intolerant.
However, there are abundant of dairy products surrounding us, so there's a
mismatch between environment and human. thrifty genotype=get fat really fast when intake high
EX: Pima tribe. They are stuck between 2 powerful tribe.
They are constantly nutrient-deficient. Bacterial evolution
is much faster. Both figures from Gluckman et al (2009) Evolved Defenses May Be Harmful
Evolution has given us powerful immune defenses
But, excessive reactions can cause harm:
• Fever (pyrexia) can cause seizures, brain damage
• Allergies, asthma, anaphylaxis
• Autoimmune disease
common diseases are hypothesize to due or link to symbiotic organism in
our body. This is known as hygeine hypothesis: humans coevolve with
microbiota Hygeine hypothesis suggest co-evolution with microbiota:
the advent of antibiotics eliminate not only harmful bacteria but also beneficial
bacteria, so along with decrease in measles, tuberculosis, hepatitis A, we have
increase of autoimmune disease (Crohn's...
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This document was uploaded on 03/09/2014 for the course EXSC 301 at USC.
- Spring '09