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Unformatted text preview: mone bind to carrier protein because they are not very soluble in
aqueous solutions. that fraction of lipophilic hormone that is unbound can diffuse directly through the membrane and bind to cytoplasmic or nuclear receptor to become activated transcription factor
that can affect gene expression.
3. a recent discovered variant of the 2 classic pathway above: certain steroid hormone bind to specific plasma membrane receptor and exert action on cell via second messenger system. seen in
progesterone and receptors for progesterone. Altered Enzymes,
Channels, or Gene
Hormone RESPONSE 1
Protein Cytoplasmic receptor 2 RESPONSE Signal
need to know role amplification play Amplification
& Phosphatases Fig. 6-8 Types of Membrane Receptors
there are just 4 major categories of membrane receptors:
1. ligand-gated ion channel
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This document was uploaded on 03/09/2014 for the course EXSC 301 at USC.
- Spring '09