4-Cell Communication Figs BW

Receptor enzyme 3 g protein coupled progesterone

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Unformatted text preview: ein coupled (progesterone membrane receptor) 4. integrin Ligand-gated ion channel Receptorenzyme G-protein coupled* Integrin receptors ECF ICF *Progesterone membrane receptor is this type Fig. 6-4 we start with ligand-gated ion channel. before that though we need to review how cells use electrochemical gradient to generate signals. in any situation where there's an unequal distribution of ions across the membrane AND that membrane have open ion channel, then a membrane potential difference will develop. in the situation where only one ion is permeable and if you allow the system to come to equilibrium (occur in an instant), then the membrane potential difference that develop will be shown through nerst equation (no.9). vm ( membrane potential) will equal some constant. R (gas constant) T (absolute temperature) F Z (valence) are constant. IF the different set of ion channel open, then the membrane will assume new values and generate electrical signal Ionic Basis of Resting Membrane Potential ICF ECF low K+ Cl- Na+ high Na+ ClK+ high K+ ClATP K+ low Na+ Cl- concentration electrical K+ +Resting Membrane Potential 1. Na/K ATPase ( ) creates ionic concentratio...
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