4-Cell Communication Figs BW

Viagra inhibits phosphodiesterase that break down

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Unformatted text preview: ion is terminated by diffusion of NO away and also activate phosphodiesterase that degrade cGMP to regular GMP. so is an inhibitor phosphodiesterase, which prolong erection. Nitric Oxide: • Synthesized from arginine ENZYME Guanuyl cyclase catalyze GTP to cGMP, which is a signaling molecule. cGMP level increase, and stimulate protein kinase G-dependent cGMP, which phosphorylate target protein and mediate its effects. NO is a common neurotransmitter. neuromodulator (a chemical signal, usually paracrine, in the nervous tissue that affects the activity of nerve cells and affects the action of other signal molecules, like other neurotransmitter), so as neuromodulator, regulate and enhances/inhibits other signal rather than being a signal itself. in the brain. in the intestine it's responsible for relaxation phase of peristalsis (waves of contractions that propel the intestinal content along length of intestine, or mixing movements)-participate in cyclic contraction and relaxation phase (here) of intestine. relax smooth muscle, leading to vasodilation. so if you relax arterile smooth muscle and more...
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This document was uploaded on 03/09/2014 for the course EXSC 301 at USC.

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