ABIO Lecture 12 6 slides per page

ABIO Lecture 12 6 slides per page - Lipids Biological...

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2/17/13 1 Lipids • Biological macromolecules that do not dissolve in H 2 O •Mostly ___________ component A. Variety of lipids e.g., Steroids - flat rings- non polar (Cell ___________________; precursor to steroid hormones) (male hormone) (Calcium and phosphorus absorp=on) (Stress response) B. Fatty Acids 1. Component of many other lipids 2. Amphipathic H ___________ _________________ 3. Good components of _________ -Can solubilize “greasy” (non polar) material -Can interact with H 2 O can wash- off with water Sodium Dodecyl Sulfate (_______) CH 3 (CH 2 ) O SO 3 11 -Use to __________ _______ can interact with hydrophobic residues in proteins Shampoos Na=ve Protein SDS Denatured Protein
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2/17/13 2 SDS Polyacrylamide Gel electrophoresis (SDS PAGE) SDS Size standards H + Top BoLom ±arger proteins slower Smaller proteins migrate faster Saturated Fatty Acids “Quadruple*Bypass Burger” ________ ______ are mostly saturated hLp://www.bing.com/videos/search?q=heart+aLack+grill&mid=36035F116FD47128964D36035 F116FD47128964D&view=detail&FORM=VIRE3 Non polar tails easily stack together by hydrophobic interactions. Saturated Fatty Acids: Hydrocarbon tails _______________ _______________ lard solid at room temperature Clogged Artery Saturated Fatty Acids Unsaturated Fatty Acids
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2/17/13 3 5. Unsaturated Fatty Acids a) Hydrocarbon tails _______________with H atoms b) Double bonds formed c) Distortion in 3-D structure d) Tails do not interact with other tails as easily ________ __________ e) Oily fats (corn,oil, olive oil) liquid at room temperature f) “Healthier” for diet C. Triglycerides ( triacylglycerides ) H — O — C — (CH 2 ) — CH 3
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ABIO Lecture 12 6 slides per page - Lipids Biological...

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