Lecture Notes 2

Lecture Notes 2 - Lecture 2 1/10/08 Biosc 0350 Genetics...

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Lecture 2 1/10/08 1 Biosc 0350 Genetics Lecture 2 - Patterns of inheritance (1) 1) Mendel’s Breakthrough Monohybrid crosses - Law of Segregation Dihybrid crosses - Law of Independent Assortment 2) Genetic bookeeping Punnett square Branch diagrams 3) Using probability to predict progeny Product rule Sum rule 4) Chi square analysis (Chapter 5) 1/10/2008 Martens. Biosc 0350, University of Pittsburgh 2 How do we explain the inheritance of traits? — Mendel’s revolutionary experiments Gregor Mendel 1860’s - Particulate inheritance Laws of Mendelian genetics 1. Law of segregation: The two alleles for each trait separate (segregate) during gamete formation, and then unite at random, one from each parent, at fertilization. 2. Law of independent assortment: During gamete formation, different pairs of alleles segregate independently of each other. Hartwell et al , 3rd ed. Figure 2.2
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Lecture 2 1/10/08 2 1/10/2008 Martens. Biosc 0350, University of Pittsburgh 3 Keys to Mendel’s success! 1. Choice of model system - Pisum sativum (pea plant) Properties • inexpensive and many varieties were readily available self -pollination and cross -pollination diploid genome • easy to grow • short generation time • many off-spring o Hartwell et al , 3rd ed. Figure 2.7
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This note was uploaded on 04/07/2008 for the course BIOSC 0350 taught by Professor Josephmartens during the Spring '08 term at Pittsburgh.

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Lecture Notes 2 - Lecture 2 1/10/08 Biosc 0350 Genetics...

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