Food Chemistry 1

dna repair unrefined grains fortified cereal meat

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Unformatted text preview: tryptophan) Pellagra = "rough skin" in Italian Skin inflammation, heartburn, nausea, liver damage HN O Sources O HN O RDA NH2 Deficiency Toxicity Pyridoxine Vitamin B6, pyridoxal, pyridoxamine Biologically active form Function pyridoxal phosphate (PLP) Sources RDA Coenzyme for transamination reactions, esp. AAs (neurotransmitters) Decarboxylation of carboxylic acids Wheat, corn, egg yolk, liver, potato, banana, fish, chickpeas 1.31.7 mg Induced by TB drug isoniazid (supplement given) Dermatitis, fatigue Depression, confusion Convulsions, seizures Microcytic hypochromic anemia Epidemic in 1950s Neurological disorders at > 2 g /day Deficiency Toxicity Biotin B7 Biologically active form H S HN OH Function Binds to lysine residue of enzyme Cofactor in carboxylation reactions, carrier of CO2 (acetylCoA to malonyl CoA, synthesis of fatty acids) Regulation of gene expression Almost all food, esp. milk, egg yolk, tomato, almond, peanuts, avocado, mushroom Also synthesized by intestinal bacteria At least 30 g/day Deficiency does not occur naturally unless eat 20 raw egg whites per day (protein avidin binds biotin irreversibly and excreted) Why raw? O N H H O Sources RDA Defi...
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This document was uploaded on 03/13/2014 for the course CHEM 4201 at Clayton.

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