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Unformatted text preview: r Mn Cu, Zn, I, Fe F Acrodermatitis enteropathica Goiter Vitamins Organic compounds Necessary for metabolic processes Insufficient synthesis in the body Recommended Daily Values Fatsoluble Watersoluble
Figure from Lippincott's Biochemistry, 2nd ed., 1994 Vitamins Watersoluble Thiamine Riboflavin Niacin Pyridoxine Biotin Folic acid Cobalamin Ascorbic acid Pantothenic acid Fatsoluble Vitamin A Vitamin D Vitamin K Vitamin E Thiamine Vitamin B1 Biologically active form Function thiamine pyrophosphate (TPP) Also can have TTP cofactor in oxidative decarboxylation of keto acids (TCA, AA degradation) RC(O)COOH to RC(O)OH + CO2 Other coenzymes also involved in process Role of B1: H between S and N is very acidic; when removed makes an ylide pork, whole grains, legumes, tuna, soy milk 0.5 mg/1000 Cal intake or min 1 mg/day req. increase with high carb diet or elevated metabolic needs decreased ATP production impaired cellular function BeriBeri Wern...
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