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Unformatted text preview: ickeKorsakoff Syndrome, aka "cerebral BeriBeri"
O P O P O O O S HO S N+ H2N N N ATP Sources RDA AMP N+ Deficiency O O H2N N N Riboflavin Vitamin B2; vit G? Biologically active forms Function Flavin mononucleotide (FMN) Flavin adenine dinucleotide (FAD) Electron transfer FMNH2, FADH2 Redox reactions (TCA, glycolysis, etc.) Needed for good vision and healthy skin Milk, mushrooms, tomatoes, liver, green leafy vegetables 1.11.3 mg/day Growth retardation Ariboflavinosis OH OH OH OH N N O Sources RDA NH N O Deficiency Cheilosis Glossitis Stomatitis Niacin Nicotinic acid, Vitamin B3 Biologically active forms Function NAD+, Nicotinamide adenine dinucleotide NADP+ Nicotinamide (readily deaminated, also in diet) Coenzymes in redox reactions (TCA, FA synthesis, gluconeogenesis, etc.) DNA repair Unrefined grains, fortified cereal, meat, fish, tomatoes, mushrooms, milk, liver, rice Metabolism of tryptophan when AA is abundant (needs riboflavin and B6) 1416 NE/day (NE = niacin equivalents = 1 mg niacin or 60 mg...
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