Notes for Microbio Lab Quiz 7 - Notes for Microbio Lab Quiz...

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Notes for Microbio Lab Quiz 7 Antimicrobial Control 1. Biological 3. mechanical - antibiotics - filtration - phages - antimicrobial coating - bacteriocins -sharklet - biotherapy - probiotics 2. physical 4. chemical - temperature -growth - ph -synthetic drugs - uv -natural compounds - osmotic pressure Antibiotics: treating infections internally Antiseptics: food preservation and personal hygiene Disinfectants: cleaning reagents Gram Pos. and Gram Neg. 1. modes to inhibit growth - cell wall polymerization - replication, transcription, translation - membrane integrity 2. modes of bacterial resistance - drug resistant enzymes - alteration of target site - drug resistant plasmid Ways to classify antibiotics 1. Effect on cells - bacteirostatic (stops cell growth ) - bactericidal (kills) 2. range of activity - broad vs. narrow spectrum 3. therapeutic index - ratio of dose toxic to host to effective therapeutic dose. Higher index= better antibiotic 4. sites of activity
- inhibition of cell wall, protein, nucleic acid, metabolites synthesis - injury to plasma membrane

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