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To form this structure the sequence must be

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Unformatted text preview: ture: random coil. There is flexibility of rotation of residues and no specific structure. •  Stacked-base structure: adapted by non– self-complementary single strands under “native” conditions. Bases stack to pull the chain into a helix, but there is little Hbonding. •  Hairpin structures: formed by selfcomplementary sequences; the chain folds back on itself to make a stem–loop structure. Plasticity of Nucleic Acids •  Self ­complementarity in a base sequence allows a chain to fold back on itself and form a base ­paired, anDparallel helix or hairpin structure •  Double hairpins, ojen called cruciform (cross ­like) structures, can form in some DNA/RNA sequences. •  •  To form this structure, the sequence must be palindromic. Self ­complementarity dictates the ter.ary structure of tRNA. Plasticity of Secondary and Tertiary DNA Structure Structures of DNA! Triplex G ­Quadruplex Structures of DNA! Holliday Junc.on RNA Structure •  RNA molecules are usually single ­s...
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