MCDB1A-F2007-christoffersen-part4-4pg - Molecular Biology...

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Molecular Biology and Medicine Chpt.
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Genetic Basis of Disease
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Genetic Markers
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RFLP mapping
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Human Genome Project
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Genetic Screening
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Gene Therapy
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Figure 17.3
Genetic Diseases of Membrane Proteins: Cystic Fibrosis
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Figure 17.6
A Fragile-X Chromosome at Metaphase
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Figure 17.10 The CGG Repeat in the Fragile-X Gene Expands with Each Generation
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Figure 17.7
Strategies for Isolating Human Genes
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Figure 17.8
RFLP Mapping (Part 1)
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Figure 17.8
RFLP Mapping (Part 2)
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Animation 17.1
DNA Testing by Allele-Specific
Cleavage
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Constructing a Genetic Linkage Map.
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Primer on Molecular Genetics
Denise Casey (Department of Energy)
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Genetic Markers
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Linkage relationships can be very useful for predicting genetic outcomes
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If two genes are linked, the inheritance of one allele is closely associated with the inheritance of the allele of the other gene located on the same chromosome.