Lecture+40_Endocrine5

Primary smulus for secreon is increase in blood

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Unformatted text preview: ce pancrea?c polypep?de •  Insulin and glucagon: –  most important in regula?ng fuel metabolism ANIMATION: Hormones and Glucose Metabolism To play movie you must be in Slide Show Mode PC Users: Please wait for content to load, then click to play Mac Users: CLICK HERE Insulin •  Lowers blood glucose, faNy acids, and amino acids by promo?ng cellular uptake. •  Anabolic: cells then use these to make other stuff •  e.g. glycogen, triglycerides, and proteins. •  Primary s?mulus for secre?on is increase in blood glucose concentra?on. •  Secre?on is increased during absorp>ve state during and aRer a meal ATP- sensi>ve K+ channel (closes) 4 ATP 5 Votage- gated Ca2+ channel (oxida>on) 3 K+ in cell because less leaves (depolariza>on) 6 Glucose- 6- phosphate 2 GLUT- 2 Glucose Glucose 7...
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This note was uploaded on 03/21/2014 for the course NPB 101 taught by Professor Fuller,charles/goldberg,jack during the Spring '08 term at UC Davis.

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