Lecture+40_Endocrine5_Revised-2

83 of the us populaon as of 2010 cdc 174 billion cost

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Unformatted text preview:   Glucose is moved into cells by the membrane glucose transporter (GLUT). •  Many varia?ons of GLUT. •  GLUT- 4 is the only type that responds to insulin. •  GLUT- 4 is not present in the plasma membrane in the absence of insulin. •  Insulin promotes GLUT- 4 inser>on into cell membrane. World J Diabetes. Jul 15, 2010; 1(3): 68–75. Glucagon •  Glucagon is secreted during the postabsorp>ve state when blood glucose declines. –  Mobilizes energy- rich molecules from their stores. –  Increases blood glucose levels. •  In general opposes the ac?ons of insulin. Diabetes Mellitus •  Diabetes M...
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