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Unformatted text preview: BIPN 102, MAMIVIALIAN PHYSIOLOGY 11 NAME: Adﬁ Egg K‘E y
Fall 2006 lst MIDTERM "EXAM 1.1). # October 19, 2006 Page 1 1. (2; points) Match each of the following situations with the correct pair of corresponding
pressures. Pairs of pressures can be used more than once, and some pairs of pressures may not be
used at all. Assume all events occur at sea level. (All pressures are in mm Hg.) Indicate which
muscles are contracting, or none, for each situation. _ a. Pu: = 760 PA = 757 f. Pm = 760 PA = 760
b. Pu: = 735 PA = 742 '3. Pa» = 790 PA = 797
c. PIP=757 PA=76I I  h. Pn=742 Pa=735
d. Pn>=797 PA=79O i. PIP=761 Pa=757
e. PIP = 775 PA = 760 j. P]? = 757 PA = 760 ex .
C A. Darin a tidal ' iration. N0 #5
2 _ g yr: 84 M” J B. At Functional Residual Capacity. NW6 +. co. "
If (“in E C. A broken rib punctures the pleural membranes. (ENE 9}? i“ die
or  ' ‘
“:2“; D. When dynamic compression of the airways is most likely to occur. :3th M1 mls 4 ml: MWl‘EQ‘; 01’ . ‘ ..
M? i E. At the beginning of a forced inspiration. dfaleQSH) 944+: l“‘1“0054ﬁ’04;5a emezwﬁﬁﬁs
Q F. Towards the end of a forced expiration. GJDAO Minds 4 {ﬂier “60 13"“le I.) G. At the end of a tidal expiration. 91w €,_ 2. (10 points). A UCSD student travels to the milehigh city of Denver, Colorado Tests and
subsequent calculations reveal that his PAOz = 76 mm Hg. Assume a normal value of PACOz and
that the student is on a diet of mainly carbohydrates. What are his P102 and the atmospheric
pressure at Denver? Show your calculations. ‘ BIPN 102, MAMMALIAN PHYSIOLOGY 11 NAME: ﬁABM/ER K5)!
Fall 2006 lst MIDTERM EXAM ID. # October 19, 2006 Page 2 3 (8 points) The graph below is a spirometer tracing of a healthy person. Name each of the lettered
vertical lines. A. EXPIRAmey EFSEWE VOLUME (61995.1;0NCT1010M. RESUJUAL am“? (We) B. ‘RGSIW VOLUME (W) 1:. ngmmae/ {fESEWé VOLUH€ (HEY)
c Tome. LUNG— CAPAC:‘)"/ (11¢) G_ “ﬁgmmmy CAPAC'W
D. VIT’H'L CHM”)! CV6) H. “THEM. VOLUME Note: There is an error in the graph: Line (E) should only reach the point after a tidal
expiration. Please shift line (E) about 1/4 inch to the right and shorten it to only reach the
trough, not the peak. Vol
(MI)
5800 2800
2300 H“.ﬂl*“*‘l .3. 1200 4 14 . Mints Fill in the followin chart 1' indicatin “increased, decreased, or normal”. Parameter Emphysema Coal Miner with Miner’ s
Lun_ Disease —m_mw
mag.1—
m— qﬂ; m Pm?9UY€ «GIMA. (live/9 ,it ' BIPN 102, MAMMALIAN PHYSIOLOGY 11 NAME: N5 6 Fall 2006 lst MIDTERM EXAM 1D. #
October 19, 2006 Page 3 5. (8 points). The lungs can contract abut 8fold if all their air is taken out after a maximum
inspiration Assume that the average alveolar radius .decreases 2fold. A. Write the LaPlace equation, naming each term of the equation, and calculate the change in
alveolar pressure when the lungs are deﬂated as above, assuming the alveoli are spherical, and that
they have no surfactant. Assume a] u . t the pressure = 1 before deﬂation. Tl“ W539“! 46‘)ka as 714%
realms clechﬁAE/J '16 ﬂ B. Name the main active component of lung surfactant (you may use initials) and indicate which
parameter of the equation it affects, and in which direction (increase or decrease). DIPALMITDYLVWDSVH ATIDYLcr—iouwe  DWC) a lwsfhoiip'tci W 3 ca 'i'ewoiea Hans em, ' minute/K
3+ decreases WW and” PM “—3 6. (6 points). You ﬁnd an alien who has an airway radius 2 times bigger than that of a normal
person. The length of the alien’s respiratory tract is also 4 times bigger than that of a normal person. Assuming that a normal person needs a pressure gradient of 1 mm Hg for airﬂow during tidal
respiration, what must the alien’s pressure gradient be to give the same ﬂow as in a normal person? Write the Poiseuille equation and show your calculations. . qr ‘f ‘t ‘f— : 774 MW
riowsz. 7" 1Y'2 rue ) I (7’) 941
7T 7. (6 points). Consider a student whose tidal volume is SOOmL with a dead space of 150mL and
breathing rate of 10 breaths/minute. Upon encountering a difﬁcult question on the midterm worth a
lot of points, her breathing rate increases to 30 breaths/minute. What must her tidal volume be so
that her PACOz remains constant? Show your calculations. spiel/Qt to 264.!» BIPN 102, MAMMALLAN PHYSIOLOGY II NAME: ANS’kléﬁ KE¥
Fall 2006 lst MIDTERMEXAM 1.1). #
October 19, 2006 Page4 8. (ll points). For the following conditions indicate whether gas exchange (diffusion) in the lungs
will be increased or decreased and which parameteds) of Fick’s equation will be affected: ' . t 1— P ’A‘
A Breathing 100% oxygen: WWW hem 'H'Q; Aggy, W 9390:, 31%;!)
[‘ 4580 Clawf marl042 $4.1 “3,95
P31" clam evereem emawr We bcmﬁh PMOJiOﬁdchﬁ/JM A1632.
B indhyperfgyysnia: 01th be“ u 12 gwdw w U49 Jet/famed
2 lea W ‘
? “ﬁgﬁﬁﬁmﬂﬁlme decrease. hem WW LoAll WW (pulmonary edema) 9. (9 points). Indicate whether the following structures wiil constrict or dilate under the conditions below:
brain pulmonary bronchioles:
arterioles: arterioles: 4" +
k 09v»; EC]
. 4r 1' AA la.
A. Breathing 100% oxygen: C0319 *6 Allele CNSLEE? dtlolg
U}. hYPOxia and hypercapnia: A: [ “Je aaWSMEf c1! l (1:16 C: High Altitude: 1 wk B. Severe emphysema with 10 (12 points) A. List three different factors that inerease Hboxygen dissociation in exercising muscle:
‘2, pa ea
B. List three different factors that increase oxygen delivery to the tissues after adaptation to high altitude: ? 2 3 DPQ’) T ERWPD'ET‘N (H1mn3 lie 1919134 CBVLCQHMHUPQ We Marmaldm  ' BIPN lOZ;MAlv1MALIAN PHYSIOLOGY II NAIVIE: A ”I 3 W66? g?
Fall 2006 lst MEDTERM EXAM 1D. # October 19,2006 Page5 l l (10 points). Diagram the mechanism by which the plasma concentration of chloride changes In
in the lung capillaries. Include the chemical reaction and transport substrates and products and the direction of their changes.
mar him W ”C03 MM “‘1 See Fig {<3 w Jim on stir/arm 4% 601
i715 [ﬁrl'biaou’vw m3~r5€0i ...
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