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DNA Replication during S phase

Helicase unwinds the dna to expose the single strands

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Unformatted text preview: to mix with lighter nitrogen. Cells in n14 one generation: o 15/14 even As the replication continues, the n15 is removed DNA semiconservative. Helicase unwinds the DNA to expose the single strands. Bi- directional replication, as there are two replication forks. The E. coli genome takes 40 minutes to replicate 4.6 mBP Drosophila takes 20 minutes to replicate 120 mBP. DNA polymerase is catalyzing the polymerization of the newly forming DNA strands Polymerases add nucleotides in the 5’ to 3’ direction. The don’t just polymerize in the 5 to 3’ direction. o They can also reverse course and remove nucleotides (exonuclease activity) in the 3’ to 5’ direction o Pr...
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