Frequency dependent selection what if the fitness of

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Unformatted text preview: = 1) Mutation selection balance There is an equilibrium frequency of deleterious alleles that depends on s and h It is a dynamic equilibrium: different alleles come and go, but the frequencies stay the same The equationeering allows us to estimate mutation rates or selection coefficients from knowledge of the incidence of disease. Handedness: Lefties are screwed. The right hand allele would seem to be more fit, but there are high rates of left handedness that would seem to be greater than the equilibrium between selection and mutation. Frequency dependent selection What if the fitness of a genotype depends on its frequency in the population? What if the fitness of a genotype changes when the allele frequency changes? w = f(p) The fitness of the genotypes depends on the...
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This document was uploaded on 03/23/2014 for the course BIOL 185 at Georgetown.

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