Removes immune complexes the others help form the

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: ways converge at C3 The terminal event are identical and common to each of the pathways. The chemotactic factors (purple): C3a, C5a, C4a There is a receptor on phagocytic cells for C5a C3b is an opsonin, assists phagocytes in taking up pathogen. Removes immune complexes. The others help form the membrane attack complex. This is a greater detail of the initiaing events. The MB- lectin is the same as C1q MASP1 = C1r MASP 2 = C1s Spontaneous hydrolysis = tickover If it finds a pathogen, can generate convertase. If not, inactivated. From the early intiation events to the middle of the cascade, there are 3 potent chemotactic factors. Released by the 2 innate pathways as soon as the pathogen breaches the epithelium. MB lectin in tissue fluid, C3b elsewhere. Immediate ac...
View Full Document

Ask a homework question - tutors are online