Removes immune complexes the others help form the

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Unformatted text preview: ways converge at C3 The terminal event are identical and common to each of the pathways. The chemotactic factors (purple): C3a, C5a, C4a There is a receptor on phagocytic cells for C5a C3b is an opsonin, assists phagocytes in taking up pathogen. Removes immune complexes. The others help form the membrane attack complex. This is a greater detail of the initiaing events. The MB- lectin is the same as C1q MASP1 = C1r MASP 2 = C1s Spontaneous hydrolysis = tickover If it finds a pathogen, can generate convertase. If not, inactivated. From the early intiation events to the middle of the cascade, there are 3 potent chemotactic factors. Released by the 2 innate pathways as soon as the pathogen breaches the epithelium. MB lectin in tissue fluid, C3b elsewhere. Immediate ac...
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