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What we find here is the recruitment of the nadph

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Unformatted text preview: these substances. There is a sort of conservation between the contents of the lysosomes and the specific granules. There are a number of signals that the phagocytic cell receives while this is going on. One of these, as we’ll see later, is a small peptide from prokaryotic proteins called fMLP. C3a and C5a bind to their receptors and the ligation of those receptors and others signals a cell to undergo something called the respiratory burst. What we find here is the recruitment of the NADPH oxidase in the cytosol and other components from the cytosol and membrane in the membrane of the phagolysosome. They start generating oxygen radicals. One of the first things that happens is vasodilation. This slows blood flow, allowing cellular elements that under normal conditions flow down the center of the vessel, drop out of the axial st...
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