Cellular Locations of TLRs

Most are acting on the vascular epithelium facilitate

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: dendritic cell. Upregulation of costimulatory molecules CD80 and 86 More cell adhesion molecules More chemokine receptors on the dendritic cell, attracted to the lymph node. They start to direct themselves to the paracortical area of the lymph node. Their job is to interact with a naïve CD4 T cell The macrophages role is to recruit additional cells to initiate acute inflammation It releases a number of pro- inflammatory cytokines. These are the most important. The macrophage cytokines are both local and systemically (3 on the left). Most are acting on the vascul...
View Full Document

This document was uploaded on 03/23/2014 for the course BIOL 358 at Georgetown.

Ask a homework question - tutors are online