Cellular Locations of TLRs

There is also going to be release of proteins from

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Unformatted text preview: ar epithelium. Facilitate the release of cells and plasma proteins. Bring in reinforcements to the site of infection. Upregulate cell adhesion molecules on the endothelium, permeability, and what we don’t see in this picture: the mast cell (contributes to the initiation of inflammation) Primarily, these IL are acting on the vascular endothelium. CF recruits additional cells. IL- 12 activates NK, important in antiviral host defense. The 3 cytokines on the left act on distant organs, one of which is the hypothalamus. This resets the body te...
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This document was uploaded on 03/23/2014 for the course BIOL 358 at Georgetown.

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