If the cell damage is irreversible necrosis is often

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Unformatted text preview: hypothalamus Tumor (swelling) the exudation of fluid and inflammatory cells from blood into tissues causes local swelling, mediated by vascular permeability due to histamine Dolor (pain) stretching and touching adds to pressure, stimulates sensory nerves Rubor (redness) increased blood flow in response to mediator, greater leakage of plasma causing increased pressure and swelling Stimulation of the phospholipid bilayer starts the metabolic pathway for the production of prostaglandins and leucotrienes. If the cell damage is irreversible, necrosis is often associated with tissue damage. Heal and resolve is the desired outcome. What pathological stimuli can cause inflammation? Overactive immune system: autoimmune Cell injury or death: necrosis Increased cellular activity: hypertrophy Dec...
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