Organization

Enzyme has two binding sites active regulatory b

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Unformatted text preview: Rna AAAAA) BBBBB) correction is the it is the “ANTI- SENSE strand” CCCCC) mRNA: n c DDDDD) EEEEE) FFFFF) GGGGG) Sense and Antisense are reversed. HHHHH) IIIII) Types of Metabolic Reactions JJJJJ) A) Chemical reactions: anabolic, catabolic a. Anabolic is synthesis, catabolic is breakdown (the reverse of each other) KKKKK) B) Hydrolysis and condensation a. Hydrolysis: A- B + H2O A- OH + H- B b. Condensation: A- OH + H- B A- B + H2O LLLLL) C) Oxidation- reduction a. Oxidation is the removal of electrons, typically by the addition of oxygen to form water b. Reduction is the addition of electrons (or H) MMMMM) D) Phosphorylation and dephosphorylation a. Phosphorylation: A + Pi A- P b. Dephosphorylation: A- P A + Pi Substrate Specificity and Induced- Fit Active site approximately fits substrates As substrate (s) begins to bind, conformation Change in enzyme allows for better fit Reaction takes place Ligand- Protein Interactions: Affinity B induces a fit, thus has a lower affinity. NNNNN) OOOOO) Regulation of Enzyme Activity PPPPP) Allosteric regulation Q...
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This document was uploaded on 03/23/2014 for the course BIOL 175 at Georgetown.

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