Cell Membrane Transport

Leukotrienes thromboxanes synthesis and release

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Unformatted text preview: ion by chemical properties (solubility, chemical class) Terminology: Ligand” a chemical messenger Source: cells which reproduce the ligand Target: has receptors for and responds to messenger Source Ligand Target Classification by Function **Pheromone: by air/scent** Paracrine, Autocrine, Neurotransmitter, Hormone/Neurohormone Paracrine: for a nearby cell Autocrine: the cell that secretes the messenger is also the target cell Neurotransmitter: released into the synaptic cleft, short distance as receptor is on next neuron Hormone: endocrine cells, long distance transport Classification by chemical properties: Solubility (lipophobic/hydrophilic vs. lipophilic/hydrophobic) Classification by Solubility Lipophobic/hydrophilic ligand: Not lipid soluble; is water soluble Does not easily cross cell membrane, may require pumps/channels Receptors on cell membrane General action of target response Enzyme activation Membrane Permeability changes Lipophilic/hydrophobic ligand: Lipid soluble, not water soluble Easily crosses cell membrane Receptor location within cell (intracellular location) in order to direct movement once inside cell General action of target response is via gene ac...
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This document was uploaded on 03/23/2014 for the course BIOL 175 at Georgetown.

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