1-Introduction

Hand washing in chlorine solumon solve the problem

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Unformatted text preview: black death (plague, Yersinia pes-s) killed 30- 60% of Europe populaMon at the end of 14c. –  Fungal disease of potatoes (blight, Phytophtora infestans) led to the potato famine in Ireland and more than a million people died of starvaMon in the 1840s. –  Typhoid fever contributed to the decline of Athens (430 BC). •  Poor medical knowledge prior to the 19c led too: –  Inacurate theories to explain infecMous disease causes/outbreaks, such as the miasma theory. –  Use of inappropriate treatment, for example bleeding, which cause more damage. –  “Witch- hunt” and persecuMon based on ethnicity and/or religion. •  17c: Could disease be due to invisible organisms ? – contagion (19c). Germ theory •  1847: Ignaz Semelweis showed that puerperal sepsis, childbed fever, is contagious. The medical students were transporMng the “cadaveric principles” from the morgue to the clinic. Hand washing in chlorine soluMon solve the problem. •  Pasteur experiments also showed that microorganisms were present in the air, a possible source of infecMon. –  Led to development of effecMve sterilizaMon procedure and pasteurizaMon. –  Pasteur also developed vaccines for mulMple diseases, such as anthrax, fowl cholera and rabies. –  1885: first successful administraMon of vaccine against rabies. •  •  Joseph Lister reported in 1867 that death due to infecMon could be reduced dramaMcally if diluted phenol was used to soak the medical devices and surgical dressing and to spray the general area during surgery. 1884: Robert Koch...
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