1-Introduction

Mid 1600s francesco redi demonstrated that maggots did

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Unformatted text preview: k Biology of Microorganisms, 13th EdiMon. Spontaneous generaMon •  Hypothesis that some vital force can create living organisms from inanimate object. It was widely accepted throughout the middle ages and into the later half of the 19c, because it fiSed nicely with the religious views of most people. •  Some recipes: –  Box + Rags + Grain = mice. –  Meat + warm temperature = maggots. –  Old apartment + student + not washing the dishes, #*@! Exams = cockroaches. •  Mid 1600s: Francesco Redi demonstrated that maggots did not developed from meat if the meat was protected by a fine gauze cover. •  Late 1700s: Lazzaro Spallanzani demonstrated that nothing grew in liquids that were boiled and stored in closed containers. The proponents of spontaneous generaMon argue that a free supply of air was required for the “vital force” to reach the liquid. 5 Louis Pasteur classic experiment (1861) Steam, forced out open end Nonsterile liquid poured into flask Neck of flask drawn out in flame Dust and microorganisms trapped in bend Liquid sterilized by extensive heating Open end Long time Liquid cooled slowly Liquid remains sterile indefinitely Short time Flask tipped so microorganism-laden dust contacts sterile liquid Liquid putrefies 6 Brock Biology of Microorganisms, 13th EdiMon. The role of infecMous diseases •  InfecMous diseases have been a major cause of mortality and morbidity throughout history. But before the 19c, the true cause of infecMous diseases was unknown. •  InfecMous disease have influenced poliMc, economy, religion, science and literature. –  An outbreak of...
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