Antibiotics are ineffective most successful and

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Unformatted text preview: are tolerant: •  Lack target sites (i.e. no pep4doglycan) •  Modify target sites •  Lack of uptake mechanism •  Some microorganisms are resistant to some an4bio4cs. An4bio4c resistance mechanism: •  Destruc4on or modifica9on of the an9bio9c (i.e. β- lactamase) •  Modifica4on of the target site •  Modifica4on of uptake mechanism •  Efflux pumps: reduce intracellular concentra4on Inactivation / Modification Brock Biology of Microorganisms, 13th Edition. Acquisi4on of resistance •  Usually mediated by the acquisi4on of a new gene (or groups of genes) that provide the cells with a new func4on (i.e. an4microbial resistance)....
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This note was uploaded on 03/20/2014 for the course PSYC 101 taught by Professor Catone during the Spring '07 term at CSU Fullerton.

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