6-Control_of_Microorganisms_Feb7

Antibiotics are ineffective most successful and

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: are tolerant: •  Lack target sites (i.e. no pep4doglycan) •  Modify target sites •  Lack of uptake mechanism •  Some microorganisms are resistant to some an4bio4cs. An4bio4c resistance mechanism: •  Destruc4on or modifica9on of the an9bio9c (i.e. β- lactamase) •  Modifica4on of the target site •  Modifica4on of uptake mechanism •  Efflux pumps: reduce intracellular concentra4on Inactivation / Modification Brock Biology of Microorganisms, 13th Edition. Acquisi4on of resistance •  Usually mediated by the acquisi4on of a new gene (or groups of genes) that provide the cells with a new func4on (i.e. an4microbial resistance)....
View Full Document

Ask a homework question - tutors are online