First a plus strand rna must be syntheezed by a viral

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Unformatted text preview: The genomes of RNA viruses will usually be replicated in the cytoplasm of the cell. Brock Biology of Microorganisms, 13th EdiEon. DNA genome •  Example: Herpesvirus •  PenetraEon: fusion of the cell cytoplasmic membrane with virus envelope. Nucleocapsid is transported to the nucleus where viral DNA is uncoated. •  Host transcripEon/translaEon apparatus syntheEzes: Immediate early proteins (transcripEon factors and, in some cases, virus- specific RNA polymerase). –  Delayed early proteins (viral- specific DNA polymerase, and other viral proteins necessary for replicaEon. –  Late proteins: nucleocapsid –  •  Assembly occurs in the nucleus, envelope is added via a budding process through the inner membrane of the nucleus. The complete virions are then secreted out of the cell by the ER pathway. •  ssDNA genome: first converted to a dsDNA replicaEve form. Brock Biology of Microorganisms, 13th EdiEon. RNA genome: 1. plus- strand RNA •  Example: Poliovirus, SARS, HepaEEs A virus. •  In Poliovirus, the plus- stra...
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This note was uploaded on 03/20/2014 for the course PSYC 101 taught by Professor Catone during the Spring '07 term at CSU Fullerton.

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