9-Taxonomy_Viruses_Feb26

High expression of the oncogene aects the regulaeon of

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Unformatted text preview:   •  Example: HIV. Causing cancer: Rous sarcoma virus. •  The virion carries two idenEcal copies of the genome (plus- strand ssRNA), reverse transcriptase, integrase and proteases. •  The reverse transcriptase is an RNA- dependent DNA polymerase that reverse transcribes the RNA genome into DNA. •  LTR: long terminal repeats. Contain promoters for transcripEon and parEcipate in the integraEon process. •  Provirus: integrated viral DNA. Contrary to the lambda prophage, the provirus cannot excise from the host genome. Consequences of virus infecEon in animal cells Brock Biology of Microorganisms, 13th EdiEon. Brock Biology of Microorganisms, 13th EdiEon. Cell fusion •  Enveloped viruses that fuse with the host cell cytoplasm carries viral proteins that fuse biological membranes. •  Cell fusion results in hybrid cells that have chromosomal aberraEons, and are usually short- lived. Oncogenic/tumor- producing viruses •  Some viral infecEon...
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