Midterm 1 Study Guide Questions

In what way does the huntingtin gene in a person

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Unformatted text preview: to the host. Opportunistic means that the organism is able to spread quickly in a previously unexploited habitat. What is ergosterol and why is it a good target for an anti- fungal drug? Ergosterol is required to complete fungal cell membranes. It is a good target for an anti- fungal drug because there ergosterol is created when nystastin binds to it. There exists a drug called fluconazole that inhibits the synthesis of nystastin to ergosterol. How do people become exposed to Histoplasma capsulatum, the fungus that causes histoplasmosis? People become exposed to Histoplasma capsulatum, which is found in soil and bat/bird dung, when they inhale airborne spores which infect their lungs. Lecture 7 What is a genetic disease? A genetic disease is caused by an abnormality in an individual’s DNA. Name three types of genetic diseases, and provide an example for each. Single- gene disorders – Hemophilia Chromosomal abnormalities – Turner’s syndrome Multifactorial disorders – Alzheimer’s disease What is a single- gene disorder? A single- gene disorder occurs when a mutation causes the protein product of a single gene to be altered or missing. This leads to a transcription error (DNA is incorrectly transcribed to mRNA). What are some examples of DNA mutations that can cause changes in the amino acid sequence of a protein? Cystic fibrosis is the result of an DNA mutation in the CFTR gene that causes changes in the amino acid sequence of the protein phenylalanine. An example of an autosomal dominant disorder is: a) Huntington’s disease, b) phenylketonuria, c) tuberculosis, or d) cooties. a) Huntington’s disease What condition is...
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